Kyrene Rd & Guadalupe Rd
Stop 14221 · Phoenix Valley Metro · Route 66
Kyrene Rd & Guadalupe Rd is a bus stop on the Phoenix Valley Metro network (stop 14221), served by Route 66 to Downtown Tempe/ASU. On weekdays buses run from 5:14 am to 10:47 pm.
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Scheduled times. The first bus of the day leaves at 5:10 am.
Route 66 to Downtown Tempe/ASU
Monday to Friday, 48 buses
| 5 am | 1444 |
|---|---|
| 6 am | 14294459 |
| 7 am | 14294459 |
| 8 am | 13274257 |
| 9 am | 1242 |
| 10 am | 1242 |
| 11 am | 1242 |
| 12 pm | 1242 |
| 1 pm | 1242 |
| 2 pm | 1242 |
| 3 pm | 124257 |
| 4 pm | 12274257 |
| 5 pm | 12274257 |
| 6 pm | 122944 |
| 7 pm | 1747 |
| 8 pm | 1747 |
| 9 pm | 1747 |
| 10 pm | 1747 |
Saturday, 36 buses
| 5 am | 1040 |
|---|---|
| 6 am | 1040 |
| 7 am | 1040 |
| 8 am | 1040 |
| 9 am | 1040 |
| 10 am | 1040 |
| 11 am | 1040 |
| 12 pm | 1040 |
| 1 pm | 1040 |
| 2 pm | 1040 |
| 3 pm | 1040 |
| 4 pm | 1040 |
| 5 pm | 1040 |
| 6 pm | 1040 |
| 7 pm | 1040 |
| 8 pm | 1040 |
| 9 pm | 1040 |
| 10 pm | 1040 |
Sunday, 35 buses
| 5 am | 1040 |
|---|---|
| 6 am | 1040 |
| 7 am | 1040 |
| 8 am | 1040 |
| 9 am | 1040 |
| 10 am | 1040 |
| 11 am | 1040 |
| 12 pm | 1040 |
| 1 pm | 1040 |
| 2 pm | 1040 |
| 3 pm | 1040 |
| 4 pm | 1040 |
| 5 pm | 1040 |
| 6 pm | 1040 |
| 7 pm | 1040 |
| 8 pm | 1040 |
| 9 pm | 1040 |
| 10 pm | 10 |
Read each row as the hour, then the minutes past it: 7 then 05 35 means 7:05 and 7:35. Bold hours are pm. Scheduled times from Phoenix Valley Metro’s official schedule data, refreshed October 4, 2026. Not live arrivals.
Questions about Kyrene Rd & Guadalupe Rd
Which buses stop at Kyrene Rd & Guadalupe Rd?
Route 66 to Downtown Tempe/ASU stops at Kyrene Rd & Guadalupe Rd (stop 14221) in Phoenix Valley Metro.
When is the first and last bus at Kyrene Rd & Guadalupe Rd?
Monday: first bus 5:14 am, last 10:47 pm (48 buses). Saturday: first bus 5:10 am, last 10:40 pm (36 buses). Sunday: first bus 5:10 am, last 10:10 pm (35 buses). Public holiday schedules can differ; each route page lists them.
How often do buses come to Kyrene Rd & Guadalupe Rd?
On a Monday about 3 buses an hour stop here between 7:00 am and 7:00 pm (34 in those twelve hours, all routes together).
What other stops are near Kyrene Rd & Guadalupe Rd?
The closest are Guadalupe Rd & Kyrene Rd (14137, about 1 min walk), Guadalupe Rd & Kyrene Rd (14197, about 1 min walk), Kyrene Rd & Guadalupe Rd (14257, about 1 min walk).
Are these live arrival times?
No. They are the scheduled times from Phoenix Valley Metro’s published schedule, refreshed October 4, 2026. A bus can run early or late, and disruptions are not shown.
Source: Valley Metro open data (GTFS schedule for Phoenix Valley Metro), used under the ODC Attribution License. Refreshed October 4, 2026; the current timetable runs to January 24, 2027. Changes made: times reformatted into timetables and departure lists.